for years i had used reference.manager, then switched to end.note a few years ago (the same time i started using a 12" powerbook). both are excellent programs, now owned by the same company. however, these days i find myself searching through pubmed and the ncbi molecular biology databases with regularity -- and the web interface modules of the aforementioned software are kludgy (at best)...
somewhere along the line i stumbled upon zotero! what a treat!! a firefox extension (you DO use firefox, right?), it may be one of the best web apps i've seen in a long time. it will integrate sets of references into different folders, even keeping track of attachments (like those long lost pdf files), abstracts and your own notes.
all this and more, howie.
the data are maintained in a sqlite database (though i would have placed the database in an easier-to-backup location) and are exportable into a variety of formats: including endnote and will also easily integrate with openoffice!
now, if 'they' can only make zotero a web2.0 app -- with shareable databases.
i would catch the vapors...
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